MEMY-496
Tissue Engineering

Syllabus

Tissues, organs and organ systems: Structure of tissues, organs and organ systems. Case studies.
Introduction and major concepts: Introduction – major concepts of tissue engineering.
Biomaterials in tissue engineering: Types, fabrication, characteristics, modification, characterization, case studies.
Stem cells in tissue engineering: Types, characterization, case studies.
Drug delivery systems: Drug delivery systems.
Biofabrication: Methods, hardware, case studies.
Mathematical modelling: Mathematical modelling in tissue engineering: solid mechanics, fluid mechanics, dynamic systems. Overview of relevant software.
Applications in regenerative medicine: Applications of tissue engineering in regenerative medicine: cases of induced regeneration in the therapy of tissue loss or organ function loss.
Applications in drug delivery: Applications of tissue engineering in drug delivery: concepts, technologies, characterization, case studies.
In vitro tissue organs: Applications of tissue engineering in in vitro tissue organs: types, technologies, case studies.

Upon successful completion of the course, students will be able to:

Get acquainted with the structure of various tissues, organs and organ systems.
Get acquainted with basic principles of developmental biology.
Know the components of tissue constructs: biomaterials, cells and bioactive molecules.
Know the various types of biomaterials utilized in tissue engineering.
Know the basic biology and applications of stem cells in tissue engineering.
Know the basic biofabrication methods utilized in tissue engineering.
Know the basic principles of mechanics (solid mechanics, fluid mechanics, dynamics) that describe tissue constructs.
Know the major experimental means used for tissue construct characterization.
Gain exposure to the state of the art of the major applications of tissue engineering: emphasis on regenerative medicine grafts, drug delivery systems, in vitro tissue models.